課程資訊
課程名稱
專題討論
Seminar 
開課學期
102-2 
授課對象
生化科技研究所  
授課教師
楊啟伸 
課號
BST7000 
課程識別碼
B22 M0020 
班次
04 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一7,8(14:20~16:20) 
上課地點
農化一第六 
備註
必修4學期與許瑞祥、黃慶璨、張麗冠、陳進庭、林晉玄合開
限碩士班以上
總人數上限:42人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1022BST7000_04 
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課程概述

專題討論 

課程目標
待補 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
2/17  <mark>課程資訊、上學期回顧、排課初版</mark> 
第2週
2/24  <mark>中英口頭報告指引</mark> 
第3週
3/03  <mark>【彭柏鈞】:博士班畢業公開演講 <br />
光動力觸發微脂體化療藥物輸送系統之臨床前研究<br />
Preclinical investigation of liposomal chemotherapy triggered by photodynamic treatment </mark> 
第4週
3/10  <mark>【蔡宜珍】:博士班畢業公開演講 <br />
組蛋白乙醯化修飾於光動力致壓效應所引發促存活分子表達之機制探討及應用 <br />
Histone acetylation involves in the increased expression of prosurvival molecules by photodynamic therapy: mechanistic investigation and clinical implication. <br />
【陳嗣民】:博士班畢業公開演講<br />靈芝子實體萃取物對三氯化鋁誘導大鼠大腦病變的療效<br />
Efficacy of <i>Ganoderma tsugae</i> Fruit Extract in Treating Aluminum Trichloride-induced Brain Dysfunction in Rats</mark>
 
第5週
3/17  <mark>【黃翔弘(博士班)】Bacteria–autophagy interplay:a battle for survival <br /><i><b>Nat Rev Microbiol. 12(2):101-14 (2014)</i></b>. <br />
【陳昱伶(博士班)】Virus-like particles: the future of microbial factories and cell-free systems as platforms for vaccine development. <br /><b><i> Current Opinion in Biotechnology 24(6):1089-1093 (2013)</i></b>.</mark> 
第6週
3/24  <mark>【黃睦晴】(博士班) TGF-beta in CAF-mediated tumor growth and metastasis. <br /><i><b>
Seminars in Cancer Biology, In Press, Corrected Proof, Available online 7 January 2014</i></b><br />
<BODY BGCOLOR="#0000FF” TEXT="#0000FF”>
以下碩一期刊文章報告</BODY><br />
【張芝榕】:
Macrophage Migration Inhibitory Factor De&#64257;ciency Is Associated With Impaired Killing of Gram-Negative Bacteria by Macrophages and Increased Susceptibility to Klebsiella pneumoniae Sepsis. <br /><b><i>The Journal of Infectious Diseases 207: 331-339, 2013 </i></b>.
<br />

【陳佩君】:HAMP domain signal relay mechanism in a sensory rhodopsin-transducer complex.
<br /><b><i>J Biol Chem. 287(25):21316-21325 (2012)</b></i>.</mark> 
第7週
3/31  <mark>【楊尉屏】:HINCUTs in cancer: hypoxia-induced noncoding ultraconserved transcripts.
<br /><b><i>Cell Death Differ. 20(12):1675-87 (2013) </b></i>.<br />
【許巧青】:An Extracellular Bacterial Pathogen
Modulates Host Metabolism to Regulate
Its Own Sensing and Proliferation. <br /><i><b>Cell 156(1): 97-108 (2014)</i></b>.</mark> 
第8週
4/07  <mark>【陳筱儒】:Photocurrent generation based on a light-driven proton pump in an artificial liquid membrane.
<br /><i><b>Nature Chem. 6(3):202-207 (2014)</i></b>.<br />
【林佳葳】:Antibiotic treatment of Pseudomonas aeruginosa biofilms stimulates expression of the magnesium transporter gene mgtE. <br /><i><b> Microbiology 160: 165-178, (2014)<b><i>.</mark> 
第9週
4/14  <mark>【張雯涵】:Small but Crucial: The Novel Small Heat Shock Protein Hsp21 Mediates Stress Adaptation and Virulence in Candida albicans. <br /><i><b>PLoS ONE 7(6):e38584 (2012) </i></b>.<br />
【蔡曉涵】:Cooperative role of RanBP9 and P73 in mitochondria-mediated apoptosis. <br /><i><b> Cell Death Dis. 4:e476 (2013)</i></b>.</mark> 
第10週
4/21  <mark>【連耿汶(博士班)】Quantitative assessment of the effectiveness of intervention steps to reduce the risk of contamination of ready-to-eat baby spinach with Salmonella
<br /><b><i>Food Control 31:410-418 (2013)</b></i>.
<br />
以下碩二碩士論文研究報告 <br />
【李盺南】:Investigation of the putative transcription factors involved in TGF-beta mediated CLIC4 expression<br />
【賴亭薇】:Molecular mechanisms involve in CLIC4 ediated MMP9 expression </mark> 
第11週
4/28  <mark>【管彥民】:Investigate the biological effect of DNA methylation on G-quadruplex of hTERT gene<br />
【黃彥鈞】:Establishment of high-throughput screening system using fluorescent-activated cell sorter in <i>Pichia pastoris</i> </mark> 
第12週
5/05  <mark>【蔡沛賜】:Regulation of the white spot syndrome virus wssv108 promoter by Litopenaeus vannamei transcription factor YY1<br />【韓怡安】:Characterization of a considered new species of halophilic archaeon isolated from Beimen saltern by physiological and biochemical analysis with rhodopsin sequence identification </mark> 
第13週
5/12  <mark>【黃筱茜】:The effects of BSLF1 on capsid proteins of Epstein-Barr virus <br />
【謝宛伶】:Analysis of α-helix and β-sheet within GMI-L6C, a mutative immunomodulatory protein from <i>Ganoderma microsporum</i>.
</mark> 
第14週
5/19  <mark>【蔡存傑】: Development and application of a new photocurrent method to characterize two proposed bacteriorhodopsins from <i>Haloquadratum walsbyi</i><br />【鄭仁華】:A Novel Function for Hog1 MAP kinase in Control of White-Opaque Switching and Its Stability in <i>Candida albicans</i></mark> 
第15週
5/26  <mark>【馮資惠】: The interplay between Rta and capsid proteins of Epstein-Barr virus<br />

【劉冠廷】:A proposed bacteriorhodopsin from <i>Haloquadratum walsbyi</i> genome project turns out to be a more sensory-like microbial rhodopsin </mark>
 
第16週
6/02  端午節
 
第17週
6/09  <b>Speaker:</b> Dr. Chien-Tsun Kuan</br>

<b>Title:</b> Next-Gen Immunotherapeutics: from Conception to Clinical Reality in Brain Tumors 
第18週
6/16  【黃庭儀】:Regulation of the immediate-early genes of white spot syndrome virus by <i>Litopenaeus vannamei YY1</i><br />
【梁慎桓】:Insight into the role of Hog1 signaling cascade Sln1-Ssk1-Ssk2-Pbs2 and Sho1 osmosensor in the regulation of white-opaque switching in <i>Candida albicans</i></br>
【王惠昌】:博士班畢業公開演講 <br />